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About Us
The Problem
A muscle spasm, also known as a muscle cramp, can cause significant
pain, and can arise from trauma, strain, or stress.
Current topical treatments for muscle spasms such Blue Emu and Theraworks don't treat the spasm, but rather just provide symptomatic relief. At this point, there is no FDA approved topical Anti-Spasmodic Agent on the market.
Proof of Principle
Currently, Prima has established proof-of-principle in animal studies with the help of following studies:
· Rota Rod Study · Open Field test
· Muscle contraction study after electrical stimulation with and without topical application of PI-111- showing inhibition of muscle spasm.
· Isolated muscle study - showing concentration-dependent relaxation · Anecdotal human exposure data.
· Demonstrated efficacy in a Torticollis patient (chronic neck muscle spasm in infants that causes pain and skeletal deformation).
· Torticollis is an orphan indication, and we can seek orphan drug status for PI-111.
Our Team
The company was established immediately following the production of the first ever patented topical anti-spasmodic drug. This revolutionary medication was generated by Priti Shah with the help of Mandar Shah. Priti Shah is an occupational therapist (OTR, CHT) and has worked in manual therapy for over 30 years. Mandar Shah is a PhD in Pharmaceutics and has more than 14 patents to his name. Both of the founders are seasoned in their respective fields. Priti has many pending ideas that will soon be patented and developed with the aid of investors.